IκB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD

Patients with CKD requiring dialysis have a higher risk of sepsis and a 100-fold higher mortality rate than the general population with sepsis. The severity of cardiac dysfunction predicts mortality in patients with sepsis. Here, we investigated the effect of preexisting CKD on cardiac function in m...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Chen, Jianmin, Kieswich, Julius E., Chiazza, Fausto, Moyes, Amie J., Gobbetti, Thomas, Purvis, Gareth S.D., Salvatori, Daniela C.F., Patel, Nimesh S.A., Perretti, Mauro, Hobbs, Adrian J., Collino, Massimo, Yaqoob, Muhammad M., Thiemermann, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198262/
https://ncbi.nlm.nih.gov/pubmed/27153924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015060670
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