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Targeted Protein Degradation by Small Molecules
Protein homeostasis networks are highly regulated systems responsible for maintaining the health and productivity of cells. Whereas therapeutics have been developed to disrupt protein homeostasis, more recently identified techniques have been used to repurpose homeostatic networks to effect degradat...
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| Опубликовано в: : | Annu Rev Pharmacol Toxicol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5586045/ https://ncbi.nlm.nih.gov/pubmed/27732798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010715-103507 |
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