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Targeted Protein Degradation by Small Molecules

Protein homeostasis networks are highly regulated systems responsible for maintaining the health and productivity of cells. Whereas therapeutics have been developed to disrupt protein homeostasis, more recently identified techniques have been used to repurpose homeostatic networks to effect degradat...

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Dades bibliogràfiques
Publicat a:Annu Rev Pharmacol Toxicol
Autors principals: Bondeson, Daniel P., Crews, Craig M.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586045/
https://ncbi.nlm.nih.gov/pubmed/27732798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010715-103507
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