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Conditional cell ablation by stringent tetracycline-dependent regulation of barnase in mammalian cells

Conditional expression of suicide genes in vivo has a wide range of applications in biological research and requires a minimal basal promoter activity in the uninduced state. To reduce basal activity of tetracycline (tc)-inducible target promoters we combined synthetic tet operators in varying numbe...

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Bibliografiska uppgifter
Huvudupphovsmän: Leuchtenberger, Stefanie, Perz, Angela, Gatz, Christiane, Bartsch, Jörg W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2001
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC55860/
https://ncbi.nlm.nih.gov/pubmed/11504884
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