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Stringent doxycycline dependent control of CRE recombinase in vivo

The strategy of modulating gene activities in vivo via CRE/loxP recombination would greatly profit from subjecting the recombination event to an independent and stringent temporal control. Here, we describe a transgenic mouse line, LC-1, where the expression of the cre and luciferase gene is tightly...

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Autors principals: Schönig, Kai, Schwenk, Frieder, Rajewsky, Klaus, Bujard, Hermann
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC137989/
https://ncbi.nlm.nih.gov/pubmed/12466566
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