Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis

BACKGROUND: Adenosine-to-inosine (A-to-I) editing of dsRNA by ADAR proteins is a pervasive epitranscriptome feature. Tens of thousands of A-to-I editing events are defined in the mouse, yet the functional impact of most is unknown. Editing causing protein recoding is the essential function of ADAR2,...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Heraud-Farlow, Jacki E., Chalk, Alistair M., Linder, Sandra E., Li, Qin, Taylor, Scott, White, Joshua M., Pang, Lokman, Liddicoat, Brian J., Gupte, Ankita, Li, Jin Billy, Walkley, Carl R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585977/
https://ncbi.nlm.nih.gov/pubmed/28874170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1301-4
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