Investigation of Mitochondrial Metabolic Response to Doxorubicin in Prostate Cancer Cells: An NADH, FAD and Tryptophan FLIM Assay

Prostate cancer (PCa) is one of the leading cancers in men in the USA. Lack of experimental tools that predict therapy response is one of the limitations of current therapeutic regimens. Mitochondrial dysfunctions including defective oxidative phosphorylation (OXPHOS) in cancer inhibit apoptosis by...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Alam, Shagufta Rehman, Wallrabe, Horst, Svindrych, Zdenek, Chaudhary, Ajay K., Christopher, Kathryn G., Chandra, Dhyan, Periasamy, Ammasi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585313/
https://ncbi.nlm.nih.gov/pubmed/28874842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10856-3
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