Targeted error-suppressed quantification of circulating tumor DNA using semi-degenerate barcoded adapters and biotinylated baits

Ultrasensitive methods for rare allele detection are critical to leverage the full potential offered by liquid biopsies. Here, we describe a novel molecular barcoding method for the precise detection and quantification of circulating tumor DNA (ctDNA). The major benefits of our design include straig...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Alcaide, Miguel, Yu, Stephen, Davidson, Jordan, Albuquerque, Marco, Bushell, Kevin, Fornika, Daniel, Arthur, Sarah, Grande, Bruno M., McNamara, Suzan, Tertre, Mathilde Couetoux du, Batist, Gerald, Huntsman, David G., Cavallone, Luca, Aguilar, Adriana, Basik, Mark, Johnson, Nathalie A., Deyell, Rebecca J., Rassekh, S. Rod, Morin, Ryan D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585219/
https://ncbi.nlm.nih.gov/pubmed/28874686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10269-2
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi