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C9ORF72 is a GDP/GTP exchange factor for Rab8 and Rab39 and regulates autophagy
Amyotrophic Lateral Sclerosis and Frontotemporal Dementia (ALS-FTD) are devastating neurodegenerative disease affecting motoneurons from the spinal chord and neurons from the frontal and temporal cortex, respectively. The most common genetic cause for ALS-FTD is an expansion of GGGGCC repeats within...
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| Udgivet i: | Small GTPases |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5584738/ https://ncbi.nlm.nih.gov/pubmed/27494456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1212688 |
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