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C9ORF72 is a GDP/GTP exchange factor for Rab8 and Rab39 and regulates autophagy

Amyotrophic Lateral Sclerosis and Frontotemporal Dementia (ALS-FTD) are devastating neurodegenerative disease affecting motoneurons from the spinal chord and neurons from the frontal and temporal cortex, respectively. The most common genetic cause for ALS-FTD is an expansion of GGGGCC repeats within...

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Detalhes bibliográficos
Publicado no:Small GTPases
Main Authors: Corbier, Camille, Sellier, Chantal
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584738/
https://ncbi.nlm.nih.gov/pubmed/27494456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1212688
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