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C9orf72’s Interaction with Rab GTPases—Modulation of Membrane Traffic and Autophagy
Hexanucleotide repeat expansion in an intron of Chromosome 9 open reading frame 72 (C9orf72) is the most common genetic cause of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). While functional haploinsufficiency of C9orf72 resulting from the mutation may play a role in ALS/FT...
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| Udgivet i: | Front Cell Neurosci |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5053994/ https://ncbi.nlm.nih.gov/pubmed/27774051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00228 |
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