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Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors
A key requirement for Rab function in membrane trafficking is site-specific activation by GDP-GTP exchange factors (GEFs), but the majority of the 63 human Rabs have no known GEF. We have performed a systematic characterization of the 17 human DENN domain proteins and demonstrated that they are spec...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2958468/ https://ncbi.nlm.nih.gov/pubmed/20937701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201008051 |
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