Induction of Mitochondrial Biogenesis Protects against Acetaminophen Hepatotoxicity

Mitochondrial biogenesis (MB) is an adaptive response to maintain metabolic homeostasis after mitochondrial dysfunction. Induction of MB during APAP hepatotoxicity has not been studied. To investigate this, mice were treated with toxic doses of APAP and euthanized between 0 and 96h. At early time po...

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Dettagli Bibliografici
Pubblicato in:Food Chem Toxicol
Autori principali: Du, Kuo, Ramachandran, Anup, McGill, Mitchell R., Mansouri, Abdellah, Asselah, Tarik, Farhood, Anwar, Woolbright, Benjamin L., Ding, Wen-Xing, Jaeschke, Hartmut
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584682/
https://ncbi.nlm.nih.gov/pubmed/28827156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2017.08.020
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