Induction of Mitochondrial Biogenesis Protects against Acetaminophen Hepatotoxicity

Mitochondrial biogenesis (MB) is an adaptive response to maintain metabolic homeostasis after mitochondrial dysfunction. Induction of MB during APAP hepatotoxicity has not been studied. To investigate this, mice were treated with toxic doses of APAP and euthanized between 0 and 96h. At early time po...

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Détails bibliographiques
Publié dans:Food Chem Toxicol
Auteurs principaux: Du, Kuo, Ramachandran, Anup, McGill, Mitchell R., Mansouri, Abdellah, Asselah, Tarik, Farhood, Anwar, Woolbright, Benjamin L., Ding, Wen-Xing, Jaeschke, Hartmut
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584682/
https://ncbi.nlm.nih.gov/pubmed/28827156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2017.08.020
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