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Induction of Mitochondrial Biogenesis Protects against Acetaminophen Hepatotoxicity

Mitochondrial biogenesis (MB) is an adaptive response to maintain metabolic homeostasis after mitochondrial dysfunction. Induction of MB during APAP hepatotoxicity has not been studied. To investigate this, mice were treated with toxic doses of APAP and euthanized between 0 and 96h. At early time po...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Food Chem Toxicol
Päätekijät: Du, Kuo, Ramachandran, Anup, McGill, Mitchell R., Mansouri, Abdellah, Asselah, Tarik, Farhood, Anwar, Woolbright, Benjamin L., Ding, Wen-Xing, Jaeschke, Hartmut
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584682/
https://ncbi.nlm.nih.gov/pubmed/28827156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2017.08.020
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