Induction of Mitochondrial Biogenesis Protects against Acetaminophen Hepatotoxicity

Mitochondrial biogenesis (MB) is an adaptive response to maintain metabolic homeostasis after mitochondrial dysfunction. Induction of MB during APAP hepatotoxicity has not been studied. To investigate this, mice were treated with toxic doses of APAP and euthanized between 0 and 96h. At early time po...

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Опубликовано в: :Food Chem Toxicol
Главные авторы: Du, Kuo, Ramachandran, Anup, McGill, Mitchell R., Mansouri, Abdellah, Asselah, Tarik, Farhood, Anwar, Woolbright, Benjamin L., Ding, Wen-Xing, Jaeschke, Hartmut
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584682/
https://ncbi.nlm.nih.gov/pubmed/28827156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2017.08.020
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