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Systematic Investigation of Multi-TLR Sensing Identifies Regulators of Sustained Gene Activation in Macrophages

A typical pathogen presents a combination of Toll-like receptor (TLR) ligands during infection. Although individual TLR pathways have been well characterized, the nature of this “combinatorial code” in pathogen sensing remains unclear. Here, we conducted a comprehensive transcriptomic analysis of pr...

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Detalhes bibliográficos
Publicado no:Cell Syst
Main Authors: Lin, Bin, Dutta, Bhaskar, Fraser, Iain D.C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584636/
https://ncbi.nlm.nih.gov/pubmed/28750197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.06.014
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