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Systematic Investigation of Multi-TLR Sensing Identifies Regulators of Sustained Gene Activation in Macrophages

A typical pathogen presents a combination of Toll-like receptor (TLR) ligands during infection. Although individual TLR pathways have been well characterized, the nature of this “combinatorial code” in pathogen sensing remains unclear. Here, we conducted a comprehensive transcriptomic analysis of pr...

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Bibliografiske detaljer
Udgivet i:Cell Syst
Main Authors: Lin, Bin, Dutta, Bhaskar, Fraser, Iain D.C.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584636/
https://ncbi.nlm.nih.gov/pubmed/28750197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.06.014
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