Genome-wide siRNA screen of genes regulating the LPS-induced NF-κB and TNF-α responses in mouse macrophages

The mammalian innate immune system senses many bacterial stimuli through the toll-like receptor (TLR) family. Activation of the TLR4 receptor by bacterial lipopolysaccharide (LPS) is the most widely studied TLR pathway due to its central role in host responses to gram-negative bacterial infection an...

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Publicado en:Sci Data
Autores principales: Li, Ning, Katz, Samuel, Dutta, Bhaskar, Benet, Zachary L., Sun, Jing, Fraser, Iain D.C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332015/
https://ncbi.nlm.nih.gov/pubmed/28248925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sdata.2017.8
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