Genome-wide siRNA screen for mediators of NF-κB activation

Although canonical NFκB is frequently critical for cell proliferation, survival, or differentiation, NFκB hyperactivation can cause malignant, inflammatory, or autoimmune disorders. Despite intensive study, mammalian NFκB pathway loss-of-function RNAi analyses have been limited to specific protein c...

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Detaylı Bibliyografya
Asıl Yazarlar: Gewurz, Benjamin E., Towfic, Fadi, Mar, Jessica C., Shinners, Nicholas P., Takasaki, Kaoru, Zhao, Bo, Cahir-McFarland, Ellen D., Quackenbush, John, Xavier, Ramnik J., Kieff, Elliott
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2012
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289371/
https://ncbi.nlm.nih.gov/pubmed/22308454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120542109
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