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LMP1 Transmembrane Domain 1 and 2 (TM1-2) FWLY Mediates Intermolecular Interactions with TM3-6 To Activate NF-κB

The Epstein-Barr virus oncoprotein LMP1 has six transmembrane domains (TMs) that enable intermolecular aggregation and constitutive signaling through two C-terminal cytosolic domains. Expression of both TMs 1 and 2 without the C terminus (TM1-2ΔC) and TMs 3 to 6 fused to the C terminus (TM3-6) resul...

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Detalles Bibliográficos
Main Authors: Soni, Vishal, Yasui, Teruhito, Cahir-McFarland, Ellen, Kieff, Elliott
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1641781/
https://ncbi.nlm.nih.gov/pubmed/16928765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01214-06
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