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The X-linked lymphoproliferative syndrome gene product SH2D1A associates with p62(dok) (Dok1) and activates NF-κB

The X-linked lymphoproliferative syndrome (XLP) is a genetic disorder in which affected males have a morbid or fatal response to Epstein–Barr virus infection. The XLP deficiency has been mapped to a gene encoding a 128-residue protein, SH2D1A, which is comprised principally of a Src homology 2 (SH2)...

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Detalhes bibliográficos
Main Authors: Sylla, Bakary S., Murphy, Kerry, Cahir-McFarland, Ellen, Lane, William S., Mosialos, George, Kieff, Elliott
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16569/
https://ncbi.nlm.nih.gov/pubmed/10852966
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