Epstein-Barr latent membrane protein 1 transformation site 2 activates NF-κB in the absence of NF-κB essential modifier residues 133–224 or 373–419

Epstein Barr virus latent membrane protein 1 (LMP1) induces NF-κB activation through transformation effector sites (TES) 1 and 2, both of which are critical for B-lymphocyte transformation. TES2 principally activates canonical NF-κB, which we confirm is NF-κB essential modifier (NEMO)-dependent and...

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Autores principales: Boehm, Daniela, Gewurz, Benjamin E., Kieff, Elliott, Cahir-McFarland, Ellen
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2010
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964205/
https://ncbi.nlm.nih.gov/pubmed/20923877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011752107
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