Epstein–Barr virus latent infection membrane protein 1 TRAF-binding site induces NIK/IKKα-dependent noncanonical NF-κB activation

Epstein–Barr virus (EBV) latent infection membrane protein 1 (LMP1)-induced NF-κB activation is important for infected cell survival. LMP1 activates NF-κB, in part, by engaging tumor necrosis factor (TNF) receptor-associated factors (TRAFs), which also mediate NF-κB activation from LTβR and CD40. LT...

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Bibliographic Details
Main Authors: Luftig, Micah, Yasui, Teruhito, Soni, Vishal, Kang, Myung-Soo, Jacobson, Nils, Cahir-McFarland, Ellen, Seed, Brian, Kieff, Elliott
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC314152/
https://ncbi.nlm.nih.gov/pubmed/14691250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2237183100
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