Epstein–Barr virus-transforming protein latent infection membrane protein 1 activates transcription factor NF-κB through a pathway that includes the NF-κB-inducing kinase and the IκB kinases IKKα and IKKβ

The Epstein–Barr virus oncoprotein latent infection membrane protein 1 (LMP1) is a constitutively aggregated pseudo-tumor necrosis factor receptor (TNFR) that activates transcription factor NF-κB through two sites in its C-terminal cytoplasmic domain. One site is similar to activated TNFRII in assoc...

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Bibliographic Details
Main Authors: Sylla, Bakary S., Hung, Siu Chun, Davidson, David M., Hatzivassiliou, Eudoxia, Malinin, Nikolai L., Wallach, David, Gilmore, Thomas D., Kieff, Elliott, Mosialos, George
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1998
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC21469/
https://ncbi.nlm.nih.gov/pubmed/9707608
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