Immunomodulatory action of SGI-110, a hypomethylating agent, in acute myeloid leukemia cells

The mechanism of clinical action for the FDA approved hypomethylating drugs azacitidine and decitabine remains unresolved and in this context the potential immunomodulatory effect of these agents on leukemic cells is an area of active investigation. Induced expression of methylated Cancer Testis Ant...

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Udgivet i:Leuk Res
Main Authors: Srivastava, Pragya, Paluch, Benjamin E., Matsuzaki, Junko, James, Smitha R., Collamat-Lai, Golda, Karbach, Julia, Nemeth, Michael J., Taverna, Pietro, Karpf, Adam R., Griffiths, Elizabeth A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584559/
https://ncbi.nlm.nih.gov/pubmed/25260825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2014.09.001
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