Immunomodulatory action of the DNA methyltransferase inhibitor SGI-110 in epithelial ovarian cancer cells and xenografts

We aimed to determine the effect of SGI-110 on methylation and expression of the cancer testis antigens (CTAs) NY-ESO-1 and MAGE-A in epithelial ovarian cancer (EOC) cells in vitro and in vivo and to establish the impact of SGI-110 on expression of major histocompatibility (MHC) class I and Intracel...

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Publicat a:Epigenetics
Autors principals: Srivastava, Pragya, Paluch, Benjamin E, Matsuzaki, Junko, James, Smitha R, Collamat-Lai, Golda, Taverna, Pietro, Karpf, Adam R, Griffiths, Elizabeth A
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623048/
https://ncbi.nlm.nih.gov/pubmed/25793777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1017198
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