The novel, small molecule DNA methylation inhibitor SGI-110 as an ovarian cancer chemosensitizer

PURPOSE: To investigate SGI-110 as a “chemosensitizer” in ovarian cancer (OC) and to assess its effects on tumor suppressor genes (TSG) and chemo-responsiveness associated genes silenced by DNA methylation in OC. EXPERIMENTAL DESIGN: Several OC cell lines were used for in vitro and in vivo platinum...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Fang, Fang, Munck, Joanne, Tang, Jessica, Taverna, Pietro, Wang, Yinu, Miller, David F.B., Pilrose, Jay, Choy, Gavin, Azab, Mohammad, Pawelczak, Katherine S., VanderVere-Carozza, Pamela, Wagner, Michael, Lyons, John, Matei, Daniela, Turchi, John J., Nephew, Kenneth P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268357/
https://ncbi.nlm.nih.gov/pubmed/25316809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1553
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge