The novel, small molecule DNA methylation inhibitor SGI-110 as an ovarian cancer chemosensitizer

PURPOSE: To investigate SGI-110 as a “chemosensitizer” in ovarian cancer (OC) and to assess its effects on tumor suppressor genes (TSG) and chemo-responsiveness associated genes silenced by DNA methylation in OC. EXPERIMENTAL DESIGN: Several OC cell lines were used for in vitro and in vivo platinum...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Fang, Fang, Munck, Joanne, Tang, Jessica, Taverna, Pietro, Wang, Yinu, Miller, David F.B., Pilrose, Jay, Choy, Gavin, Azab, Mohammad, Pawelczak, Katherine S., VanderVere-Carozza, Pamela, Wagner, Michael, Lyons, John, Matei, Daniela, Turchi, John J., Nephew, Kenneth P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268357/
https://ncbi.nlm.nih.gov/pubmed/25316809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1553
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