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Guadecitabine (SGI‐110) priming sensitizes hepatocellular carcinoma cells to oxaliplatin

Promoter DNA hypermethylation is an important biomarker of hepatocellular carcinoma (HCC), supporting the potential utility of demethylating agents in this disease. Guadecitabine (SGI‐110) is a second‐generation hypomethylating agent formulated as a dinucleotide of decitabine and deoxyguanosine that...

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Bibliografske podrobnosti
izdano v:Mol Oncol
Main Authors: Kuang, Yuting, El-Khoueiry, Anthony, Taverna, Pietro, Ljungman, Mats, Neamati, Nouri
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528722/
https://ncbi.nlm.nih.gov/pubmed/26160429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.06.002
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