Guadecitabine (SGI‐110) priming sensitizes hepatocellular carcinoma cells to oxaliplatin

Promoter DNA hypermethylation is an important biomarker of hepatocellular carcinoma (HCC), supporting the potential utility of demethylating agents in this disease. Guadecitabine (SGI‐110) is a second‐generation hypomethylating agent formulated as a dinucleotide of decitabine and deoxyguanosine that...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Oncol
Egile Nagusiak: Kuang, Yuting, El-Khoueiry, Anthony, Taverna, Pietro, Ljungman, Mats, Neamati, Nouri
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2015
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528722/
https://ncbi.nlm.nih.gov/pubmed/26160429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.06.002
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