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Guadecitabine (SGI‐110) priming sensitizes hepatocellular carcinoma cells to oxaliplatin
Promoter DNA hypermethylation is an important biomarker of hepatocellular carcinoma (HCC), supporting the potential utility of demethylating agents in this disease. Guadecitabine (SGI‐110) is a second‐generation hypomethylating agent formulated as a dinucleotide of decitabine and deoxyguanosine that...
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| Publicado en: | Mol Oncol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528722/ https://ncbi.nlm.nih.gov/pubmed/26160429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.06.002 |
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