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Evaluating somatic tumor mutation detection without matched normal samples

BACKGROUND: Observations of recurrent somatic mutations in tumors have led to identification and definition of signaling and other pathways that are important for cancer progression and therapeutic targeting. As tumor cells contain both an individual’s inherited genetic variants and somatic mutation...

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Vydáno v:Hum Genomics
Hlavní autoři: Teer, Jamie K., Zhang, Yonghong, Chen, Lu, Welsh, Eric A., Cress, W. Douglas, Eschrich, Steven A., Berglund, Anders E.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584341/
https://ncbi.nlm.nih.gov/pubmed/28870239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-017-0118-2
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