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Characteristics and Validation Techniques for PCA-Based Gene-Expression Signatures
Background. Many gene-expression signatures exist for describing the biological state of profiled tumors. Principal Component Analysis (PCA) can be used to summarize a gene signature into a single score. Our hypothesis is that gene signatures can be validated when applied to new datasets, using inhe...
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Publicado no: | Int J Genomics |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Hindawi Publishing Corporation
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5317117/ https://ncbi.nlm.nih.gov/pubmed/28265563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/2354564 |
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