Evaluating somatic tumor mutation detection without matched normal samples

BACKGROUND: Observations of recurrent somatic mutations in tumors have led to identification and definition of signaling and other pathways that are important for cancer progression and therapeutic targeting. As tumor cells contain both an individual’s inherited genetic variants and somatic mutation...

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Detalhes bibliográficos
Publicado no:Hum Genomics
Main Authors: Teer, Jamie K., Zhang, Yonghong, Chen, Lu, Welsh, Eric A., Cress, W. Douglas, Eschrich, Steven A., Berglund, Anders E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584341/
https://ncbi.nlm.nih.gov/pubmed/28870239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-017-0118-2
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