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Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF–mediated myelopoiesis
Myelopoiesis is necessary for the generation of mature myeloid cells during homeostatic turnover and immunological insults; however, the metabolic requirements for this process remain poorly defined. Here, we demonstrate that myelopoiesis, including monocyte and macrophage differentiation, requires...
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| Pubblicato in: | J Exp Med |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5584119/ https://ncbi.nlm.nih.gov/pubmed/28784627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161855 |
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