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mTORC1 couples immune signals and metabolic programming to establish T(reg) cell function

The mechanistic target of rapamycin (mTOR) pathway integrates diverse environmental inputs, including immune signals and metabolic cues, to direct T cell fate decisions(1). Activation of mTOR, comprised of mTORC1 and mTORC2 complexes, delivers an obligatory signal for proper activation and different...

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Bibliografski detalji
Glavni autori: Zeng, Hu, Yang, Kai, Cloer, Caryn, Neale, Geoffrey, Vogel, Peter, Chi, Hongbo
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759242/
https://ncbi.nlm.nih.gov/pubmed/23812589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12297
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