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mTORC1 couples immune signals and metabolic programming to establish T(reg) cell function

The mechanistic target of rapamycin (mTOR) pathway integrates diverse environmental inputs, including immune signals and metabolic cues, to direct T cell fate decisions(1). Activation of mTOR, comprised of mTORC1 and mTORC2 complexes, delivers an obligatory signal for proper activation and different...

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Bibliografiska uppgifter
Huvudupphovsmän: Zeng, Hu, Yang, Kai, Cloer, Caryn, Neale, Geoffrey, Vogel, Peter, Chi, Hongbo
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759242/
https://ncbi.nlm.nih.gov/pubmed/23812589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12297
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