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mTORC1 couples immune signals and metabolic programming to establish T(reg) cell function
The mechanistic target of rapamycin (mTOR) pathway integrates diverse environmental inputs, including immune signals and metabolic cues, to direct T cell fate decisions(1). Activation of mTOR, comprised of mTORC1 and mTORC2 complexes, delivers an obligatory signal for proper activation and different...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3759242/ https://ncbi.nlm.nih.gov/pubmed/23812589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12297 |
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