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Loss of Glis2/NPHP7 causes kidney epithelial cell senescence and suppresses cyst growth in the Kif3a mouse model of cystic kidney disease

Enlargement of kidney tubules is a common feature of multiple cystic kidney diseases in humans and mice. However, while some of these pathologies are characterized by cyst expansion and organ enlargement, in others, progressive interstitial fibrosis and kidney atrophy prevail. The Kif3a knockout mou...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: Lu, Dongmei, Rauhauser, Alysha, Li, Binghua, Ren, Chongyu, McEnery, Kayla, Zhu, Jili, Chaki, Moumita, Vadnagara, Komal, Elhadi, Sarah, Jetten, Anton M., Igarashi, Peter, Attanasio, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584074/
https://ncbi.nlm.nih.gov/pubmed/27181777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.03.006
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