Loss of diacylglycerol kinase epsilon in mice causes endothelial distress and impairs glomerular Cox-2 and PGE(2) production

Thrombotic microangiopathy (TMA) is a disorder characterized by microvascular occlusion that can lead to thrombocytopenia, hemolytic anemia, and glomerular damage. Complement activation is the central event in most cases of TMA. Primary forms of TMA are caused by mutations in genes encoding componen...

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Publicado no:Am J Physiol Renal Physiol
Main Authors: Zhu, Jili, Chaki, Moumita, Lu, Dongmei, Ren, Chongyu, Wang, Shan-Shan, Rauhauser, Alysha, Li, Binghua, Zimmerman, Susan, Jun, Bokkyoo, Du, Yong, Vadnagara, Komal, Wang, Hanquin, Elhadi, Sarah, Quigg, Richard J., Topham, Matthew K., Mohan, Chandra, Ozaltin, Fatih, Zhou, Xin J., Marciano, Denise K., Bazan, Nicolas G., Attanasio, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867310/
https://ncbi.nlm.nih.gov/pubmed/26887830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00431.2015
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