Experimental cardiac radiation exposure induces ventricular diastolic dysfunction with preserved ejection fraction

Breast cancer radiotherapy increases the risk of heart failure with preserved ejection fraction (HFpEF). Cardiomyocytes are highly radioresistant, but radiation specifically affects coronary microvascular endothelial cells, with subsequent microvascular inflammation and rarefaction. The effects of r...

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Опубликовано в: :Am J Physiol Heart Circ Physiol
Главные авторы: Saiki, Hirofumi, Moulay, Gilles, Guenzel, Adam J., Liu, Weibin, Decklever, Teresa D., Classic, Kelly L., Pham, Linh, Chen, Horng H., Burnett, John C., Russell, Stephen J., Redfield, Margaret M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2017
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582918/
https://ncbi.nlm.nih.gov/pubmed/28550173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00124.2017
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