Effects of Sildenafil on Ventricular and Vascular Function in Heart Failure With Preserved Ejection Fraction

BACKGROUND: Early studies showed beneficial effects of phosphodiesterase 5 inhibitors (PDE5i) on cardiovascular function in heart failure (HF) patients, but the RELAX trial observed no improvement in exercise capacity with sildenafil treatment in subjects with HF and preserved ejection fraction (HFp...

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Détails bibliographiques
Publié dans:Circ Heart Fail
Auteurs principaux: Borlaug, Barry A., Lewis, Gregory D., McNulty, Steven E., Semigran, Marc J., LeWinter, Martin, Chen, Horng, Lin, Grace, Deswal, Anita, Margulies, Kenneth B., Redfield, Margaret M.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439337/
https://ncbi.nlm.nih.gov/pubmed/25782985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.114.001915
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