Experimental cardiac radiation exposure induces ventricular diastolic dysfunction with preserved ejection fraction

Breast cancer radiotherapy increases the risk of heart failure with preserved ejection fraction (HFpEF). Cardiomyocytes are highly radioresistant, but radiation specifically affects coronary microvascular endothelial cells, with subsequent microvascular inflammation and rarefaction. The effects of r...

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Bibliographic Details
Published in:Am J Physiol Heart Circ Physiol
Main Authors: Saiki, Hirofumi, Moulay, Gilles, Guenzel, Adam J., Liu, Weibin, Decklever, Teresa D., Classic, Kelly L., Pham, Linh, Chen, Horng H., Burnett, John C., Russell, Stephen J., Redfield, Margaret M.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582918/
https://ncbi.nlm.nih.gov/pubmed/28550173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00124.2017
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