Experimental cardiac radiation exposure induces ventricular diastolic dysfunction with preserved ejection fraction

Breast cancer radiotherapy increases the risk of heart failure with preserved ejection fraction (HFpEF). Cardiomyocytes are highly radioresistant, but radiation specifically affects coronary microvascular endothelial cells, with subsequent microvascular inflammation and rarefaction. The effects of r...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Saiki, Hirofumi, Moulay, Gilles, Guenzel, Adam J., Liu, Weibin, Decklever, Teresa D., Classic, Kelly L., Pham, Linh, Chen, Horng H., Burnett, John C., Russell, Stephen J., Redfield, Margaret M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582918/
https://ncbi.nlm.nih.gov/pubmed/28550173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00124.2017
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