Experimental cardiac radiation exposure induces ventricular diastolic dysfunction with preserved ejection fraction

Breast cancer radiotherapy increases the risk of heart failure with preserved ejection fraction (HFpEF). Cardiomyocytes are highly radioresistant, but radiation specifically affects coronary microvascular endothelial cells, with subsequent microvascular inflammation and rarefaction. The effects of r...

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Pubblicato in:Am J Physiol Heart Circ Physiol
Autori principali: Saiki, Hirofumi, Moulay, Gilles, Guenzel, Adam J., Liu, Weibin, Decklever, Teresa D., Classic, Kelly L., Pham, Linh, Chen, Horng H., Burnett, John C., Russell, Stephen J., Redfield, Margaret M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582918/
https://ncbi.nlm.nih.gov/pubmed/28550173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00124.2017
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