A common NHE3 single-nucleotide polymorphism has normal function and sensitivity to regulatory ligands

Na(+)/H(+) exchanger NHE3 mediates the majority of intestinal and renal electroneutral sodium absorption. Dysfunction of NHE3 is associated with a variety of diarrheal diseases. We previously reported that the NHE3 gene (SLC9A3) has more than 400 single-nucleotide polymorphisms (SNPs) but few nonsyn...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Physiol Gastrointest Liver Physiol
Prif Awduron: Yin, Jianyi, Tse, Chung-Ming, Cha, Boyoung, Sarker, Rafiquel, Zhu, Xinjun C., Walentinsson, Anna, Greasley, Peter J., Donowitz, Mark
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582881/
https://ncbi.nlm.nih.gov/pubmed/28495802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00044.2017
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