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Tenapanor administration and the activity of the H(+)‐coupled transporter PepT1 in healthy volunteers
AIM: Tenapanor (RDX5791/AZD1722), an inhibitor of gastrointestinal Na(+)/H(+) exchanger NHE3, is being evaluated for the treatment of patients with constipation‐predominant irritable bowel syndrome and the treatment of hyperphosphataemia in patients with chronic kidney disease on dialysis. By reduci...
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| Publicat a: | Br J Clin Pharmacol |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5582369/ https://ncbi.nlm.nih.gov/pubmed/28432691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13313 |
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