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Effects of Tenapanor on Cytochrome P450‐Mediated Drug‐Drug Interactions

Tenapanor (RDX5791, AZD1722) is an inhibitor of sodium/hydrogen exchanger isoform 3 in development for the treatment of constipation‐predominant irritable bowel syndrome and the treatment of hyperphosphatemia in patients with chronic kidney disease on dialysis. We aimed to investigate whether tenapa...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Drug Dev
Main Authors: Johansson, Susanne, Rosenbaum, David P., Ahlqvist, Marie, Rollison, Helen, Knutsson, Mikael, Stefansson, Bergur, Elebring, Marie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599994/
https://ncbi.nlm.nih.gov/pubmed/28301096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.346
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