Efficient Killing of Murine Pluripotent Stem Cells by Natural Killer (NK) Cells Requires Activation by Cytokines and Partly Depends on the Activating NK Receptor NKG2D

Natural killer (NK) cells play an important role as cytotoxic effector cells, which scan the organism for infected or tumorigenic cells. Conflicting data have been published whether NK cells can also kill allogeneic or even autologous pluripotent stem cells (PSCs) and which receptors are involved. A...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Gröschel, Carina, Hübscher, Daniela, Nolte, Jessica, Monecke, Sebastian, Sasse, André, Elsner, Leslie, Paulus, Walter, Trenkwalder, Claudia, Polić, Bojan, Mansouri, Ahmed, Guan, Kaomei, Dressel, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582315/
https://ncbi.nlm.nih.gov/pubmed/28890717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00870
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