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NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development

The activation of natural killer (NK) cells depends on a change in the balance of signals from inhibitory and activating receptors. The activation threshold values of NK cells are thought to be set by engagement of inhibitory receptors during development. Here, we found that the activating receptor...

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Vydáno v:Nat Immunol
Hlavní autoři: Jelenčić, Vedrana, Šestan, Marko, Kavazović, Inga, Lenartić, Maja, Marinović, Sonja, Holmes, Tim D., Prchal-Murphy, Michaela, Lisnić, Berislav, Sexl, Veronika, Bryceson, Yenan T., Wensveen, Felix M., Polić, Bojan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166863/
https://ncbi.nlm.nih.gov/pubmed/30224819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0209-9
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