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Cheating the Hunger Games; Mechanisms Controlling Clonal Diversity of CD8 Effector and Memory Populations

Effector and memory CD8 T cells have an intrinsic difference in the way they must approach antigen; effector cells need to address the pathogen at hand and therefore favor outgrowth of only high-affinity clones. In contrast, the memory pool benefits from greater clonal diversity to recognize and eli...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Kavazović, Inga, Polić, Bojan, Wensveen, Felix M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281969/
https://ncbi.nlm.nih.gov/pubmed/30555492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02831
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