Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1

Human induced pluripotent stem cells (hiPSCs) could be used to generate autologous cells for therapeutic purposes, which are expected to be tolerated by the recipient. However, iPSC-derived grafts are at risk of giving rise to teratomas in the host, if residuals of tumorigenic cells are not rejected...

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Veröffentlicht in:PLoS One
Hauptverfasser: Kruse, Vanessa, Hamann, Carina, Monecke, Sebastian, Cyganek, Lukas, Elsner, Leslie, Hübscher, Daniela, Walter, Lutz, Streckfuss-Bömeke, Katrin, Guan, Kaomei, Dressel, Ralf
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423859/
https://ncbi.nlm.nih.gov/pubmed/25950680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125544
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