Susceptibility of Human Melanoma Cells to Autologous Natural Killer (NK) Cell Killing: HLA-Related Effector Mechanisms and Role of Unlicensed NK Cells

BACKGROUND: Despite Natural Killer (NK) cells were originally defined as effectors of spontaneous cytotoxicity against tumors, extremely limited information is so far available in humans on their capability of killing cancer cells in an autologous setting. METHODOLOGY/PRINCIPAL FINDINGS: We have est...

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Autors principals: Carrega, Paolo, Pezzino, Gaetana, Queirolo, Paola, Bonaccorsi, Irene, Falco, Michela, Vita, Giuseppe, Pende, Daniela, Misefari, Aldo, Moretta, Alessandro, Mingari, Maria Cristina, Moretta, Lorenzo, Ferlazzo, Guido
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780723/
https://ncbi.nlm.nih.gov/pubmed/19997637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008132
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