Susceptibility of Human Melanoma Cells to Autologous Natural Killer (NK) Cell Killing: HLA-Related Effector Mechanisms and Role of Unlicensed NK Cells

BACKGROUND: Despite Natural Killer (NK) cells were originally defined as effectors of spontaneous cytotoxicity against tumors, extremely limited information is so far available in humans on their capability of killing cancer cells in an autologous setting. METHODOLOGY/PRINCIPAL FINDINGS: We have est...

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Detalhes bibliográficos
Main Authors: Carrega, Paolo, Pezzino, Gaetana, Queirolo, Paola, Bonaccorsi, Irene, Falco, Michela, Vita, Giuseppe, Pende, Daniela, Misefari, Aldo, Moretta, Alessandro, Mingari, Maria Cristina, Moretta, Lorenzo, Ferlazzo, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780723/
https://ncbi.nlm.nih.gov/pubmed/19997637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008132
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