Killer Ig-Like Receptors (KIRs): Their Role in NK Cell Modulation and Developments Leading to Their Clinical Exploitation

Natural killer (NK) cells contribute to the first line of defense against viruses and to the control of tumor growth and metastasis spread. The discovery of HLA class I specific inhibitory receptors, primarily of killer Ig-like receptors (KIRs), and of activating receptors has been fundamental to un...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Pende, Daniela, Falco, Michela, Vitale, Massimo, Cantoni, Claudia, Vitale, Chiara, Munari, Enrico, Bertaina, Alice, Moretta, Francesca, Del Zotto, Genny, Pietra, Gabriella, Mingari, Maria Cristina, Locatelli, Franco, Moretta, Lorenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558367/
https://ncbi.nlm.nih.gov/pubmed/31231370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01179
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