Killer Ig-Like Receptors (KIRs): Their Role in NK Cell Modulation and Developments Leading to Their Clinical Exploitation

Natural killer (NK) cells contribute to the first line of defense against viruses and to the control of tumor growth and metastasis spread. The discovery of HLA class I specific inhibitory receptors, primarily of killer Ig-like receptors (KIRs), and of activating receptors has been fundamental to un...

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Publicado en:Front Immunol
Autores principales: Pende, Daniela, Falco, Michela, Vitale, Massimo, Cantoni, Claudia, Vitale, Chiara, Munari, Enrico, Bertaina, Alice, Moretta, Francesca, Del Zotto, Genny, Pietra, Gabriella, Mingari, Maria Cristina, Locatelli, Franco, Moretta, Lorenzo
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558367/
https://ncbi.nlm.nih.gov/pubmed/31231370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01179
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