Killer Ig-Like Receptors (KIRs): Their Role in NK Cell Modulation and Developments Leading to Their Clinical Exploitation

Natural killer (NK) cells contribute to the first line of defense against viruses and to the control of tumor growth and metastasis spread. The discovery of HLA class I specific inhibitory receptors, primarily of killer Ig-like receptors (KIRs), and of activating receptors has been fundamental to un...

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Publicat a:Front Immunol
Autors principals: Pende, Daniela, Falco, Michela, Vitale, Massimo, Cantoni, Claudia, Vitale, Chiara, Munari, Enrico, Bertaina, Alice, Moretta, Francesca, Del Zotto, Genny, Pietra, Gabriella, Mingari, Maria Cristina, Locatelli, Franco, Moretta, Lorenzo
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558367/
https://ncbi.nlm.nih.gov/pubmed/31231370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01179
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